‘Remdesivir is approved for emergency use by the US Food and Drug Administration (FDA) and authorized conditionally by the European Medicines Agency (EMA) for patients with coronavirus disease 2019 (COVID-19). Its benefit-risk ratio is still being explored because data in the field are rather scant.
A decrease of the creatinine clearance associated with remdesivir has been inconstantly reported in clinical trials with unclear relevance. Despite these uncertainties, we searched for a potential signal of acute renal failure (ARF) in pharmacovigilance postmarketing data.
An analysis of the international pharmacovigilance postmarketing databases (VigiBase) of the World Health Organization (WHO) was performed, using two disproportionality methods. Reporting odds ratio (ROR) compared the number of ARF cases reported with remdesivir, with those reported with other drugs prescribed in comparable situations of COVID-19 (hydroxychloroquine, tocilizumab, and lopinavir/ritonavir).
The combination of the terms "acute renal failure" and "remdesivir" yielded a statistically significant disproportionality signal with 138 observed cases instead of the 9 expected. ROR of ARF with remdesivir was 20-fold (20.3; confidence interval 0.95 [15.7-26.3], P < 0.0001]) that of comparative drugs.
Based on ARF cases reported in VigiBase, and despite the caveats inherent to COVID-19 circumstances, we detected a statistically significant pharmacovigilance signal of nephrotoxicity associated with remdesivir, deserving a thorough qualitative assessment of all available data. Meanwhile, as recommended in its Summary of Product Characteristics, assessment of patients with COVID-19 renal function should prevail before and during treatment with remdesivir in COVID-19.’
Audio of the WCH World Ivermectin Day live event 20230729: Top experts from around the world share the science, while happy patients and their families share stories of miraculous recoveries, and others share dark recollections of hospitals and governments that handed out death sentences while blocking access to safe medicine.
And many imbeciles still do not believe it, despite 40-50 million vaxx-deaths and a huge reduction in human fertility, both caused by the toxic Covid-19 "vaccines".
13 YEARS AGO JESSIE VENTURA INTERVIEWED ALEX JONES, THEN DR RIMA LAIBOW.
They warned of the UN, the WHO, the Bilderberg Group, planned pandemics, forced injections, population reduction and sterilization. This five minute clip from 2009:.
Today at 2 PM EDT Christof Plothe DO and myself M Trozzi MD, will present an update on how the covid-19 "vaccines" are performing in terms of preventing covid-19 infections and disease. Please join us and the global audience of the World Council For Health here at 2 PM today:
6170 Albertans were killed in WW1 and 2943 killed in WW2 for a total of 9113.
I calculated Alberta total Covid-19 "vaccine+lockdown"-caused deaths from 1H2021 to 1H2023 at 10,500.
So Jason and Rachel have now killed more Albertans than we lost in WW1 and WW2...
... and it looks like Danielle has bought into the scamdemic. We had better hopes for her.
From my Chapter above:
“That does not include another 500,000 avoidable American deaths in 2020, needlessly killed by late treatment, remdesivir and ventilators.”
In plain language, Remdesivir is a killer drug that blows out liver and kidneys. Part of the Great Cull.
Regards, Allan
REMDESIVIR AND ACUTE RENAL FAILURE: A POTENTIAL SAFETY SIGNAL FROM DISPROPORTIONALITY ANALYSIS OF THE WHO SAFETY DATABASE
https://pubmed.ncbi.nlm.nih.gov/33340409/
Thanks to Dr Paul Alexander
[excerpt]
‘Remdesivir is approved for emergency use by the US Food and Drug Administration (FDA) and authorized conditionally by the European Medicines Agency (EMA) for patients with coronavirus disease 2019 (COVID-19). Its benefit-risk ratio is still being explored because data in the field are rather scant.
A decrease of the creatinine clearance associated with remdesivir has been inconstantly reported in clinical trials with unclear relevance. Despite these uncertainties, we searched for a potential signal of acute renal failure (ARF) in pharmacovigilance postmarketing data.
An analysis of the international pharmacovigilance postmarketing databases (VigiBase) of the World Health Organization (WHO) was performed, using two disproportionality methods. Reporting odds ratio (ROR) compared the number of ARF cases reported with remdesivir, with those reported with other drugs prescribed in comparable situations of COVID-19 (hydroxychloroquine, tocilizumab, and lopinavir/ritonavir).
The combination of the terms "acute renal failure" and "remdesivir" yielded a statistically significant disproportionality signal with 138 observed cases instead of the 9 expected. ROR of ARF with remdesivir was 20-fold (20.3; confidence interval 0.95 [15.7-26.3], P < 0.0001]) that of comparative drugs.
Based on ARF cases reported in VigiBase, and despite the caveats inherent to COVID-19 circumstances, we detected a statistically significant pharmacovigilance signal of nephrotoxicity associated with remdesivir, deserving a thorough qualitative assessment of all available data. Meanwhile, as recommended in its Summary of Product Characteristics, assessment of patients with COVID-19 renal function should prevail before and during treatment with remdesivir in COVID-19.’
CONTRASTING IVERMECTIN WITH COVID-19 “VACCINES” ‣ DR TROZZI
https://drtrozzi.org/2023/08/01/contrasting-ivermectin-with-covid-19-vaccines/
Audio of the WCH World Ivermectin Day live event 20230729: Top experts from around the world share the science, while happy patients and their families share stories of miraculous recoveries, and others share dark recollections of hospitals and governments that handed out death sentences while blocking access to safe medicine.
PREVENT GENOCIDE 2030
Dr Rima Laibow, Co-founder
https://preventgenocide2030.org/
PREDICTED IN 2009, AND IT HAS NOW ALL HAPPENED.
And many imbeciles still do not believe it, despite 40-50 million vaxx-deaths and a huge reduction in human fertility, both caused by the toxic Covid-19 "vaccines".
13 YEARS AGO JESSIE VENTURA INTERVIEWED ALEX JONES, THEN DR RIMA LAIBOW.
They warned of the UN, the WHO, the Bilderberg Group, planned pandemics, forced injections, population reduction and sterilization. This five minute clip from 2009:.
https://drtrozzi.org/2023/07/31/the-covid-agenda-exosed-in-2009/
Today at 2 PM EDT Christof Plothe DO and myself M Trozzi MD, will present an update on how the covid-19 "vaccines" are performing in terms of preventing covid-19 infections and disease. Please join us and the global audience of the World Council For Health here at 2 PM today:
https://worldcouncilforhealth.org/newsroom/
Blessings,
-Dr Mark Trozzi
COVID & CLIMATE CHRONICLES - THE BIG CULL
This is my free book about the Covid and Climate frauds that have wasted trillions and killed tens of millions. .
INTRODUCTION AND INDEX
https://allanmacrae47.substack.com/p/covid-and-climate-chronicles-the
RESIST EVERY EFFORT TO CONTROL US
We are among the increasing number of people who are standing up to what feels like an enormous evil.
Peter and Ginger Breggin
July 27, 2023
https://gingerbreggin.substack.com/p/resist-every-effort-to-control-us